Mus musculus Gene: Mtnr1b
Summary
InnateDB Gene IDBG-135887.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtnr1b
Gene Name melatonin receptor 1B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050901
Encoded Proteins
melatonin receptor 1B
melatonin receptor 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134640:
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:15824528-15874556
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000057920 ENSMUSP00000053086
ENSMUST00000182947 ENSMUSP00000138524
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0008502 melatonin receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007623 circadian rhythm
GO:0042593 glucose homeostasis
GO:0050796 regulation of insulin secretion
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3SXF8
UniProt Splice Variant
Entrez Gene 244701
UniGene
RefSeq XM_006510273 NM_145712
OMIM
CCDS CCDS22841
HPRD
IMGT
MGI ID MGI:2181726
MGI Symbol Mtnr1b
EMBL AB377276 AC154307 AC161370 BC104324 BC104325 CH466522
GenPept AAI04325 AAI04326 BAH03531 EDL25036
RNA Seq Atlas 244701