Version 5.4
Mus musculus Gene: Dlgap2
Summary
InnateDB Gene IDBG-136312.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlgap2
Gene Name discs, large (Drosophila) homolog-associated protein 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000047495
Encoded Proteins
IDBP-136314
discs, large (Drosophila) homolog-associated protein 2
IDBP-532526
discs, large (Drosophila) homolog-associated protein 2
IDBP-534262
discs, large (Drosophila) homolog-associated protein 2
IDBP-538824
discs, large (Drosophila) homolog-associated protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198010:
The product of this gene is a membrane-associated guanylate kinase. The encoded protein may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Mar 2013]
The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:14095865-14847680
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000043279 ENSMUSP00000039647
ENSMUST00000152652 ENSMUSP00000123078
ENSMUST00000133298 ENSMUSP00000119613
ENSMUST00000150247 ENSMUSP00000123104
ENSMUST00000141155
ENSMUST00000136000
ENSMUST00000141214
ENSMUST00000137130
ENSMUST00000129119
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007267 cell-cell signaling
GO:0008150 biological_process
Cellular Component
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000198010
View Gene Order
Cross-References
SwissProt Q8BJ42
TrEMBL
UniProt Splice Variant
Entrez Gene 244310
UniGene Mm.323861 Mm.404697 Mm.475787
RefSeq XM_006508783 NM_001145965 NM_172910 XM_006508781 XM_006508782
OMIM
CCDS CCDS52491 CCDS52492
HPRD
IMGT
MGI ID MGI:2443181
MGI Symbol Dlgap2
EMBL AK032564 AY243847
GenPept AAO89218 BAC27927
RNA Seq Atlas 244310

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca