Version 5.4
Homo sapiens Gene: DLGAP2
Summary
InnateDB Gene IDBG-5385.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLGAP2
Gene Name discs, large (Drosophila) homolog-associated protein 2
Synonyms DAP2; SAPAP2
Species Homo sapiens
Ensembl Gene ENSG00000198010
Encoded Proteins
IDBP-360606
discs, large (Drosophila) homolog-associated protein 2
IDBP-478745
discs, large (Drosophila) homolog-associated protein 2
IDBP-811841
discs, large (Drosophila) homolog-associated protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is a membrane-associated guanylate kinase. The encoded protein may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Mar 2013]
The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:1501366-1708476
Strand Forward strand
Band p23.3
Transcripts
ENST00000421627 ENSP00000400258
ENST00000520901 ENSP00000430563
ENST00000522499
ENST00000524065
ENST00000518530
ENST00000612087 ENSP00000484215
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007267 cell-cell signaling
GO:0007270 neuron-neuron synaptic transmission
Cellular Component
GO:0005883 neurofilament
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000047495
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.113287 Hs.603990
RefSeq NM_001277161 NM_004745 XM_005266038
HUGO
OMIM
CCDS CCDS47760 CCDS75689
HPRD 09258
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca