Version 5.4
Mus musculus Gene: Dnaja1
Summary
InnateDB Gene IDBG-136348.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnaja1
Gene Name DnaJ (Hsp40) homolog, subfamily A, member 1
Synonyms Hsj2; Nedd7
Species Mus musculus
Ensembl Gene ENSMUSG00000028410
Encoded Proteins
IDBP-136350
DnaJ (Hsp40) homolog, subfamily A, member 1
IDBP-540120
DnaJ (Hsp40) homolog, subfamily A, member 1
IDBP-540890
DnaJ (Hsp40) homolog, subfamily A, member 1
IDBP-533644
DnaJ (Hsp40) homolog, subfamily A, member 1
IDBP-622668
DnaJ (Hsp40) homolog, subfamily A, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086061:
Gene Information
Type Protein coding
Genomic Location Chromosome 4:40722150-40737149
Strand Forward strand
Band A5
Transcripts
ENSMUST00000030118 ENSMUSP00000030118
ENSMUST00000139406
ENSMUST00000137476
ENSMUST00000129204
ENSMUST00000137246 ENSMUSP00000118294
ENSMUST00000125442 ENSMUSP00000116601
ENSMUST00000149794 ENSMUSP00000121461
ENSMUST00000126020
ENSMUST00000148976
ENSMUST00000164233 ENSMUSP00000129730
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 79 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0030544 Hsp70 protein binding
GO:0031072 heat shock protein binding
GO:0046872 metal ion binding
GO:0050750 low-density lipoprotein particle receptor binding
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
Biological Process
GO:0006457 protein folding
GO:0007283 spermatogenesis
GO:0009408 response to heat
GO:0030317 sperm motility
GO:0030521 androgen receptor signaling pathway
GO:0042769 DNA damage response, detection of DNA damage
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043508 negative regulation of JUN kinase activity
GO:0051223 regulation of protein transport
GO:0070585 protein localization to mitochondrion
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086061
View Gene Order
ENSBTAG00000016265
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
ar_tf_pathway
Regulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27897 Mm.471224
RefSeq NM_001164671 NM_001164672 NM_008298
OMIM
CCDS CCDS18049
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca