Version 5.4
Mus musculus Gene: Sema3c
Summary
InnateDB Gene IDBG-136681.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sema3c
Gene Name sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Synonyms 1110036B02Rik; Semae; SemE
Species Mus musculus
Ensembl Gene ENSMUSG00000028780
Encoded Proteins
IDBP-136683
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
IDBP-623578
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
IDBP-623585
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075223:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:17574281-17730268
Strand Forward strand
Band A3
Transcripts
ENSMUST00000030568 ENSMUSP00000030568
ENSMUST00000115271
ENSMUST00000170181 ENSMUSP00000126614
ENSMUST00000170348
ENSMUST00000169603 ENSMUSP00000132330
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0030215 semaphorin receptor binding
Biological Process
GO:0001755 neural crest cell migration
GO:0001756 somitogenesis
GO:0001974 blood vessel remodeling
GO:0003151 outflow tract morphogenesis
GO:0003215 cardiac right ventricle morphogenesis
GO:0003350 pulmonary myocardium development
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
GO:0007507 heart development
GO:0009791 post-embryonic development
GO:0021915 neural tube development
GO:0060174 limb bud formation
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
Cellular Component
GO:0005615 extracellular space
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000075223
View Gene Order
ENSBTAG00000006138
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
plexind1_pathway
Plexin-D1 Signaling
Cross-References
SwissProt
TrEMBL E9PXL2
UniProt Splice Variant
Entrez Gene 20348
UniGene Mm.397997 Mm.474031 Mm.5071
RefSeq NM_013657
OMIM
CCDS CCDS19099
HPRD
IMGT
MGI ID MGI:107557
MGI Symbol Sema3c
EMBL AC122936 AC161507
GenPept
RNA Seq Atlas 20348

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca