Version 5.4
Mus musculus Gene: Cthrc1
Summary
InnateDB Gene IDBG-136725.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cthrc1
Gene Name collagen triple helix repeat containing 1
Synonyms 1110014B07Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000054196
Encoded Proteins
IDBP-136727
collagen triple helix repeat containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164932:
This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:39076932-39087121
Strand Forward strand
Band B3.1
Transcripts
ENSMUST00000067072 ENSMUSP00000070018
ENSMUST00000132192
ENSMUST00000144800
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005109 frizzled binding
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
Biological Process
GO:0016477 cell migration
GO:0032092 positive regulation of protein binding
GO:0033690 positive regulation of osteoblast proliferation
GO:0043932 ossification involved in bone remodeling
GO:0045669 positive regulation of osteoblast differentiation
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060122 inner ear receptor stereocilium organization
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090103 cochlea morphogenesis
GO:0090177 establishment of planar polarity involved in neural tube closure
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164932
View Gene Order
ENSBTAG00000032591
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
wnt_signaling_pathway
Wnt signaling network
wnt_noncanonical_pathway
Noncanonical Wnt signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_026778
OMIM
CCDS CCDS27442
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca