Version 5.4
Mus musculus Gene: Nol6
Summary
InnateDB Gene IDBG-137054.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nol6
Gene Name nucleolar protein family 6 (RNA-associated)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028430
Encoded Proteins
IDBP-137056
nucleolar protein family 6 (RNA-associated)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165271:
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:41114427-41124455
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000030138 ENSMUSP00000030138
ENSMUST00000155315
ENSMUST00000129112
ENSMUST00000135059
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165271
View Gene Order
ENSBTAG00000003323
Not yet available
Cross-References
SwissProt Q8R5K4
TrEMBL Q3TBM4
UniProt Splice Variant
Entrez Gene 230082
UniGene Mm.285797
RefSeq NM_139236
OMIM
CCDS CCDS38715
HPRD
IMGT
MGI ID MGI:2140151
MGI Symbol Nol6
EMBL AF361077 AF361078 AK053117 AK155818 AK166650 AK171163 AL954379 BC019981 BC021856 BC059820
GenPept AAH19981 AAH21856 AAH59820 AAL74401 AAL74402 BAC35271 BAE33447 BAE38917 BAE42285 CAM27656
RNA Seq Atlas 230082

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca