Version 5.4
Mus musculus Gene: Lair1
Summary
InnateDB Gene IDBG-137073.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lair1
Gene Name leukocyte-associated Ig-like receptor 1
Synonyms 5133400O11Rik; BB115266; D7Bwg0421e; Lair-1; mLair-1
Species Mus musculus
Ensembl Gene ENSMUSG00000055541
Encoded Proteins
IDBP-137075
leukocyte-associated Ig-like receptor 1
IDBP-137077
leukocyte-associated Ig-like receptor 1
IDBP-137079
leukocyte-associated Ig-like receptor 1
IDBP-264190
leukocyte-associated Ig-like receptor 1
IDBP-401649
leukocyte-associated Ig-like receptor 1
IDBP-534977
leukocyte-associated Ig-like receptor 1
IDBP-541023
leukocyte-associated Ig-like receptor 1
IDBP-540012
leukocyte-associated Ig-like receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21151495
Lair1 play an inhibition role in the mechanisms controlling Ifna production by pDCs both in normal and pathological innate immune responses.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:4007073-4063204
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000068865 ENSMUSP00000070712
ENSMUST00000086401 ENSMUSP00000083589
ENSMUST00000086400 ENSMUSP00000083588
ENSMUST00000108600 ENSMUSP00000104241
ENSMUST00000119711 ENSMUSP00000113871
ENSMUST00000136616 ENSMUSP00000122037
ENSMUST00000149395 ENSMUSP00000116800
ENSMUST00000131126 ENSMUSP00000121738
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.398105
RefSeq NM_001113474 NM_178611 XM_006540175 XM_006540176 XM_006540177 XM_006540181 XM_006540182
OMIM
CCDS CCDS20729 CCDS51969
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca