Version 5.4
Mus musculus Gene: Agpat5
Summary
InnateDB Gene IDBG-137452.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agpat5
Gene Name 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
Synonyms 1110013A05Rik; D8Ertd319e
Species Mus musculus
Ensembl Gene ENSMUSG00000031467
Encoded Proteins
IDBP-137454
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
IDBP-536317
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155189:
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:18846277-18891361
Strand Forward strand
Band A1.3
Transcripts
ENSMUST00000033847 ENSMUSP00000033847
ENSMUST00000149565 ENSMUSP00000117025
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006639 acylglycerol metabolic process
GO:0008152 metabolic process
GO:0016024 CDP-diacylglycerol biosynthetic process
Cellular Component
GO:0005635 nuclear envelope
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000155189
View Gene Order
ENSBTAG00000004922
Not yet available
Pathways
NETPATH
REACTOME
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_237947
Triglyceride Biosynthesis pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188640
Synthesis of PA pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120906
Synthesis of PA pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9D1E8
TrEMBL F8WGD9
UniProt Splice Variant
Entrez Gene 52123
UniGene Mm.24117 Mm.384682 Mm.386475 Mm.397710 Mm.407793 Mm.408968 Mm.448401 Mm.468431
RefSeq NM_026792
OMIM
CCDS CCDS22126
HPRD
IMGT
MGI ID MGI:1196345
MGI Symbol Agpat5
EMBL AC129567 AK003649 AK082137 AK089885 AK152709 AK152889 AK155378 AY161042 BC031987
GenPept AAH31987 AAN75571 BAB22915 BAC38421 BAC40983 BAE31436 BAE31572 BAE33229
RNA Seq Atlas 52123

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca