InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Col5a3

Summary

InnateDB Gene

IDBG-137455.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col5a3

Gene Name

collagen, type V, alpha 3

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000004098

Encoded Proteins

IDBP-137457

collagen, type V, alpha 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000080573:
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:20770050-20815067

Strand

Reverse strand

Band

Transcripts

ENSMUST00000004201	ENSMUSP00000004201
ENSMUST00000145974

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005201	extracellular matrix structural constituent
GO:0008201	heparin binding
GO:0043394	proteoglycan binding