Version 5.4
Mus musculus Gene: Foxg1
Summary
InnateDB Gene IDBG-137578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxg1
Gene Name forkhead box G1
Synonyms 2900064B05Rik; BF-1; Bf1; Hfh9; Hfhbf1
Species Mus musculus
Ensembl Gene ENSMUSG00000020950
Encoded Proteins
IDBP-137580
forkhead box G1
IDBP-713420
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176165:
This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49382693-49386867
Strand Forward strand
Band B3
Transcripts
ENSMUST00000021333 ENSMUSP00000021333
ENSMUST00000135006
ENSMUST00000154930
ENSMUST00000156952
ENSMUST00000179669 ENSMUSP00000136372
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0002052 positive regulation of neuroblast proliferation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007346 regulation of mitotic cell cycle
GO:0007568 aging
GO:0009953 dorsal/ventral pattern formation
GO:0010468 regulation of gene expression
GO:0016199 axon midline choice point recognition
GO:0021852 pyramidal neuron migration
GO:0021954 central nervous system neuron development
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0030900 forebrain development
GO:0042472 inner ear morphogenesis
GO:0045665 negative regulation of neuron differentiation
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048664 neuron fate determination
GO:0048667 cell morphogenesis involved in neuron differentiation
GO:0051726 regulation of cell cycle
GO:2000177 regulation of neural precursor cell proliferation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000176165
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
smad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.4704 Mm.478178
RefSeq NM_001160112 NM_008241
OMIM
CCDS CCDS25899
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca