InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Foxg1

Summary

InnateDB Protein

IDBP-137580.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Foxg1

Protein Name

forkhead box G1

Synonyms

2900064B05Rik; BF-1; Bf1; Hfh9; Hfhbf1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021333

InnateDB Gene

IDBG-137578 (Foxg1)

Protein Structure

UniProt Annotation

Function

Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. {ECO:0000250}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

CNS, and nasal half of the retina.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0002052	positive regulation of neuroblast proliferation
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007346	regulation of mitotic cell cycle
GO:0007568	aging
GO:0009953	dorsal/ventral pattern formation
GO:0010468	regulation of gene expression
GO:0016199	axon midline choice point recognition
GO:0021852	pyramidal neuron migration
GO:0021954	central nervous system neuron development
GO:0021987	cerebral cortex development
GO:0022008	neurogenesis
GO:0030900	forebrain development
GO:0042472	inner ear morphogenesis
GO:0045665	negative regulation of neuron differentiation
GO:0045787	positive regulation of cell cycle
GO:0045892	negative regulation of transcription, DNA-templated
GO:0048664	neuron fate determination
GO:0048667	cell morphogenesis involved in neuron differentiation
GO:0051726	regulation of cell cycle
GO:2000177	regulation of neural precursor cell proliferation