Version 5.4
Homo sapiens Gene: TRIM35
Summary
InnateDB Gene IDBG-13769.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM35
Gene Name tripartite motif containing 35
Synonyms HLS5; MAIR
Species Homo sapiens
Ensembl Gene ENSG00000104228
Encoded Proteins
IDBP-13773
tripartite motif containing 35
IDBP-478072
tripartite motif containing 35
IDBP-479367
tripartite motif containing 35
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:27284887-27311319
Strand Reverse strand
Band p21.2
Transcripts
ENST00000305364 ENSP00000301924
ENST00000521283 ENSP00000429356
ENST00000521253 ENSP00000428770
ENST00000519219
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006915 apoptotic process
GO:0008285 negative regulation of cell proliferation
GO:0043065 positive regulation of apoptotic process
GO:0045087 innate immune response
GO:0045930 negative regulation of mitotic cell cycle
GO:1902187 negative regulation of viral release from host cell
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022043
View Gene Order
ENSBTAG00000009958
Not yet available
Cross-References
SwissProt
TrEMBL E5RGB3
UniProt Splice Variant
Entrez Gene 23087
UniGene Hs.104223
RefSeq XM_005273453 NM_171982 XM_005273452
HUGO HGNC:16285
OMIM
CCDS CCDS6056
HPRD 15553
IMGT
EMBL AC124649
GenPept
RNA Seq Atlas 23087

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca