Version 5.4
Mus musculus Gene: Nkrf
Summary
InnateDB Gene IDBG-138503.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nkrf
Gene Name NF-kappaB repressing factor
Synonyms 9430034D17Rik; AW124770; C80287
Species Mus musculus
Ensembl Gene ENSMUSG00000044149
Encoded Proteins
IDBP-138505
NF-kappaB repressing factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186416:
This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:36887540-36902899
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000057093 ENSMUSP00000061546
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186416
View Gene Order
ENSBTAG00000045744
Not yet available
Cross-References
SwissProt Q8BY02
TrEMBL
UniProt Splice Variant
Entrez Gene 77286
UniGene Mm.21649
RefSeq NM_029891 XM_006541409
OMIM
CCDS CCDS30065
HPRD
IMGT
MGI ID MGI:1924536
MGI Symbol Nkrf
EMBL AK020455 AK042690 AK079123 AL450399 BC138828 BC138829
GenPept AAI38829 AAI38830 BAB32107 BAC31334 BAC37550 CAM19779
RNA Seq Atlas 77286

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca