Version 5.4
Mus musculus Gene: Sept6
Summary
InnateDB Gene IDBG-138528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sept6
Gene Name septin 6
Synonyms 2810035H17Rik; C920001C06Rik; mKIAA0128; Sep6
Species Mus musculus
Ensembl Gene ENSMUSG00000050379
Encoded Proteins
IDBP-138530
septin 6
IDBP-138532
septin 6
IDBP-250071
septin 6
IDBP-537157
septin 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125354:
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:36911326-36991794
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000060474 ENSMUSP00000062014
ENSMUST00000053456 ENSMUSP00000054034
ENSMUST00000115239 ENSMUSP00000110894
ENSMUST00000152291 ENSMUSP00000116670
ENSMUST00000128766
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005819 spindle
GO:0008021 synaptic vesicle
GO:0030496 midbody
GO:0031105 septin complex
GO:0032154 cleavage furrow
GO:0043679 axon terminus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125354
View Gene Order
ENSBTAG00000004291
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt Q9R1T4
TrEMBL
UniProt Splice Variant
Entrez Gene 56526
UniGene Mm.260036 Mm.409104 Mm.470184
RefSeq NM_001177323 NM_019942 NM_001177324 NM_001253706 XM_006541389 XM_006541390
OMIM
CCDS CCDS30066 CCDS53051 CCDS57749
HPRD
IMGT
MGI ID MGI:1888939
MGI Symbol Sept6
EMBL AB023622 AK012858 AK048455 AK088406 AK088614 AK160884 AK162755 AK172894 AL450399 BC010489
GenPept AAH10489 BAA82838 BAB28516 BAC33342 BAC40335 BAC40453 BAD32172 BAE36069 BAE37050 CAM19780 CAM19781 CAM19782
RNA Seq Atlas 56526

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca