Version 5.4
Mus musculus Gene: Ndufb2
Summary
InnateDB Gene IDBG-138613.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufb2
Gene Name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
Synonyms 1810011O01Rik; 8kDa; AGGG; AI325567; CI-AGGG
Species Mus musculus
Ensembl Gene ENSMUSG00000002416
Encoded Proteins
IDBP-401447
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
IDBP-531509
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090266:
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:39592574-39603382
Strand Forward strand
Band B1
Transcripts
ENSMUST00000002490
ENSMUST00000119379 ENSMUSP00000114095
ENSMUST00000135671 ENSMUSP00000118918
ENSMUST00000146793
ENSMUST00000128064
ENSMUST00000135239
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005747 mitochondrial respiratory chain complex I
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090266
View Gene Order
ENSBTAG00000021759
Not yet available
Pathways
NETPATH
REACTOME
REACT_189162
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_262523
Respiratory electron transport pathway
REACT_188937
Metabolism pathway
REACT_261922
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
KEGG
mmu00190
Oxidative phosphorylation pathway
mmu05010
Alzheimer's disease pathway
mmu05012
Parkinson's disease pathway
mmu05016
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
REACT_215469
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_218878
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_219139
Metabolism pathway
REACT_223064
Respiratory electron transport pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt Q9CPU2
TrEMBL
UniProt Splice Variant
Entrez Gene 68198
UniGene Mm.397664 Mm.416519
RefSeq NM_026612 XM_006506529
OMIM
CCDS CCDS20025
HPRD
IMGT
MGI ID MGI:1915448
MGI Symbol Ndufb2
EMBL AK007495 AK010642 AK019008 AK028334 BC013510
GenPept AAH13510 BAB25068 BAB27084 BAB31508 BAC25887
RNA Seq Atlas 68198

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca