Version 5.4
Homo sapiens Gene: UBE2D4
Summary
InnateDB Gene IDBG-13915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2D4
Gene Name ubiquitin-conjugating enzyme E2D 4 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000078967
Encoded Proteins
IDBP-13917
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373271
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373273
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373276
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373286
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373287
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373288
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373292
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-373296
ubiquitin-conjugating enzyme E2D 4 (putative)
IDBP-594266
ubiquitin-conjugating enzyme E2D 4 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:43926438-43956136
Strand Forward strand
Band p13
Transcripts
ENST00000222402 ENSP00000222402
ENST00000450743 ENSP00000391678
ENST00000454350 ENSP00000401824
ENST00000443780 ENSP00000407196
ENST00000440899 ENSP00000410897
ENST00000415051 ENSP00000414331
ENST00000454428 ENSP00000411738
ENST00000446008 ENSP00000397406
ENST00000440652 ENSP00000406583
ENST00000473007 ENSP00000442350
ENST00000491770
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 89 experimentally validated interaction(s) in this database.
Experimentally validated
Total 89 [view]
Protein-Protein 89 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0008152 metabolic process
GO:0035519 protein K29-linked ubiquitination
GO:0044314 protein K27-linked ubiquitination
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0070979 protein K11-linked ubiquitination
GO:0085020 protein K6-linked ubiquitination
Cellular Component
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.19196
RefSeq NM_015983 XM_005249772 XM_006715737
HUGO
OMIM
CCDS CCDS5474
HPRD 14242
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca