Version 5.4
| Homo sapiens Gene: POLR2J3 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-13924.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | POLR2J3 | ||||||||||||||||||
| Gene Name | polymerase (RNA) II (DNA directed) polypeptide J3 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000168255 | ||||||||||||||||||
| Encoded Proteins |
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
polymerase (RNA) II (DNA directed) polypeptide J3
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 7:102537918-102572656 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q22.1 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME | |||||||||||||||||||
| KEGG |
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Huntington's disease pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | Hs.656696 Hs.732239 | ||||||||||||||||||
| RefSeq | NM_001097615 XM_006716033 | ||||||||||||||||||
| HUGO | |||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS47673 | ||||||||||||||||||
| HPRD | 18684 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||