InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Egln3

Summary

InnateDB Gene

IDBG-139438.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Egln3

Gene Name

EGL nine homolog 3 (C. elegans)

Synonyms

2610021G09Rik; AI505553; AI648162; Hif-p4h-3; Phd3; SM-20

Species

Mus musculus

Ensembl Gene

ENSMUSG00000035105

Encoded Proteins

IDBP-139440

EGL nine homolog 3 (C. elegans)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129521:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:54178981-54203860

Strand

Reverse strand

Band

Transcripts

ENSMUST00000039516

ENSMUSP00000041874

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418	L-ascorbic acid binding
GO:0031545	peptidyl-proline 4-dioxygenase activity

Biological Process

GO:0001666	response to hypoxia
GO:0006915	apoptotic process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974	cellular response to DNA damage stimulus
GO:0018126	protein hydroxylation
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0042127	regulation of cell proliferation
GO:0043523	regulation of neuron apoptotic process
GO:0055114	oxidation-reduction process