Bos taurus Gene: EGLN3
Summary
InnateDB Gene IDBG-632414.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EGLN3
Gene Name egl nine homolog 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008172
Encoded Proteins
egl nine homolog 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129521:
Gene Information
Type Protein coding
Genomic Location Chromosome 21:44805298-44834310
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010744 ENSBTAP00000010744
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418 L-ascorbic acid binding
GO:0031545 peptidyl-proline 4-dioxygenase activity
Biological Process
GO:0001666 response to hypoxia
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0018126 protein hydroxylation
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0042127 regulation of cell proliferation
GO:0043523 regulation of neuron apoptotic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha pathway
Cellular responses to stress pathway
Regulation of Hypoxia-inducible Factor (HIF) by oxygen pathway
Cellular response to hypoxia pathway
Cellular responses to stress pathway
Cellular response to hypoxia pathway
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha pathway
Regulation of Hypoxia-inducible Factor (HIF) by oxygen pathway
KEGG
Renal cell carcinoma pathway
Pathways in cancer pathway
Renal cell carcinoma pathway
Pathways in cancer pathway
INOH
PID NCI
HIF-1-alpha transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.33102
RefSeq NM_001101164
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas