Mus musculus Gene: Nek3 | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||
InnateDB Gene | IDBG-139892.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | Nek3 | ||||||||||||||||
Gene Name | NIMA (never in mitosis gene a)-related expressed kinase 3 | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Mus musculus | ||||||||||||||||
Ensembl Gene | ENSMUSG00000031478 | ||||||||||||||||
Encoded Proteins |
NIMA (never in mitosis gene a)-related expressed kinase 3
NIMA (never in mitosis gene a)-related expressed kinase 3
|
||||||||||||||||
Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136098:
This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] |
||||||||||||||||
Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 8:22128283-22166435 | ||||||||||||||||
Strand | Reverse strand | ||||||||||||||||
Band | A2 | ||||||||||||||||
Transcripts |
|
||||||||||||||||
Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
|
||||||||||||||||
Gene Ontology | |||||||||||||||||
Molecular Function |
|
||||||||||||||||
Biological Process |
|
||||||||||||||||
Cellular Component |
|
||||||||||||||||
Orthologs | |||||||||||||||||
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH |
Prolactin pathway
|
||||||||||||||||
REACTOME | |||||||||||||||||
KEGG | |||||||||||||||||
INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | |||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | |||||||||||||||||
UniGene | Mm.41413 | ||||||||||||||||
RefSeq | NM_001162947 NM_011848 XM_006509111 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS22169 CCDS52519 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
MGI ID | |||||||||||||||||
MGI Symbol | |||||||||||||||||
EMBL | |||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | |||||||||||||||||