Version 5.4
Mus musculus Gene: Prdm9
Summary
InnateDB Gene IDBG-140068.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prdm9
Gene Name PR domain containing 9
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000051977
Encoded Proteins
IDBP-541740
PR domain containing 9
IDBP-620790
PR domain containing 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164256:
The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation (Jiang and Huang, 2000 [PubMed 10668202]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:15543079-15564354
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000128267
ENSMUST00000130297
ENSMUST00000147532 ENSMUSP00000118454
ENSMUST00000139911
ENSMUST00000132675
ENSMUST00000167994 ENSMUSP00000131871
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0010844 recombination hotspot binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006311 meiotic gene conversion
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007126 meiotic nuclear division
GO:0007283 spermatogenesis
GO:0010845 positive regulation of reciprocal meiotic recombination
GO:0016571 histone methylation
GO:0034968 histone lysine methylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051568 histone H3-K4 methylation
GO:0060903 positive regulation of meiosis I
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000164256
View Gene Order
Pathways
NETPATH
REACTOME
REACT_27235
Meiotic Recombination pathway
REACT_200794
Mus musculus biological processes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_27271
Meiotic recombination pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q96EQ9
TrEMBL
UniProt Splice Variant
Entrez Gene 213389
UniGene Mm.215162
RefSeq NM_144809 XM_006523987 XM_006523988
OMIM
CCDS CCDS49963
HPRD
IMGT
MGI ID MGI:2384854
MGI Symbol Prdm9
EMBL AC154378 AY294423 BC012016 BC049903 CT033750
GenPept AAH12016 AAH49903 AAQ01511 CAX15894
RNA Seq Atlas 213389

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca