Version 5.4
Mus musculus Gene: Scarf2
Summary
InnateDB Gene IDBG-140230.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scarf2
Gene Name scavenger receptor class F, member 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000012017
Encoded Proteins
IDBP-140232
scavenger receptor class F, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000244486:
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:17797282-17808287
Strand Forward strand
Band A3
Transcripts
ENSMUST00000012161 ENSMUSP00000012161
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007157 heterophilic cell-cell adhesion
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000244486
View Gene Order
ENSBTAG00000019375
Not yet available
Cross-References
SwissProt P59222
TrEMBL Q58A84
UniProt Splice Variant
Entrez Gene 224024
UniGene
RefSeq NM_153790 XM_006522042 XM_006536804
OMIM
CCDS CCDS28010
HPRD
IMGT
MGI ID MGI:1858430
MGI Symbol Scarf2
EMBL AB024432 AF522197 BC139758 CH466521
GenPept AAI39759 AAN45862 BAD93344 EDK97482
RNA Seq Atlas 224024

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca