Mus musculus Protein: Scarf2
Summary
InnateDB Protein IDBP-140232.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scarf2
Protein Name scavenger receptor class F, member 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000012161
InnateDB Gene IDBG-140230 (Scarf2)
Protein Structure
UniProt Annotation
Function Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007157 heterophilic cell-cell adhesion
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1858430
InterPro IPR000742 Epidermal growth factor-like domain
IPR002049 EGF-like, laminin
IPR009030 Insulin-like growth factor binding protein, N-terminal
PFAM PF00008
PF00053
PRINTS
PIRSF
SMART SM00181
SM00180
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P59222
PhosphoSite PhosphoSite-P59222
TrEMBL Q58A84
UniProt Splice Variant
Entrez Gene 224024
UniGene
RefSeq NP_722485
MGI ID
MGI Symbol Scarf2
OMIM
CCDS CCDS28010
HPRD
IMGT
EMBL AB024432 AF522197 BC139758 CH466521
GenPept AAI39759 AAN45862 BAD93344 EDK97482