InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc22a6

Summary

InnateDB Gene

IDBG-140313.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc22a6

Gene Name

solute carrier family 22 (organic anion transporter), member 6

Synonyms

mOat1; NKT; Oat1; Orctl1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000024650

Encoded Proteins

IDBP-140315

solute carrier family 22 (organic anion transporter), member 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197901:
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:8617996-8628299

Strand

Forward strand

Band

Transcripts

ENSMUST00000010250

ENSMUSP00000010250

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005452	inorganic anion exchanger activity
GO:0005515	protein binding
GO:0008514	organic anion transmembrane transporter activity
GO:0015075	ion transmembrane transporter activity
GO:0015301	anion:anion antiporter activity
GO:0015347	sodium-independent organic anion transmembrane transporter activity
GO:0022857	transmembrane transporter activity
GO:0031404	chloride ion binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0006820	anion transport
GO:0015711	organic anion transport
GO:0015742	alpha-ketoglutarate transport
GO:0031427	response to methotrexate
GO:0034220	ion transmembrane transport
GO:0043252	sodium-independent organic anion transport
GO:0051260	protein homooligomerization
GO:0055085	transmembrane transport
GO:0097254	renal tubular secretion

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0005901	caveola
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome