Version 5.4
Mus musculus Gene: Dgcr2
Summary
InnateDB Gene IDBG-140369.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dgcr2
Gene Name DiGeorge syndrome critical region gene 2
Synonyms 9930034O06Rik; DGS-C; Dgsc; Idd; Lan; mKIAA0163; Sez12
Species Mus musculus
Ensembl Gene ENSMUSG00000003166
Encoded Proteins
IDBP-140375
DiGeorge syndrome critical region gene 2
IDBP-140377
DiGeorge syndrome critical region gene 2
IDBP-401548
DiGeorge syndrome critical region gene 2
IDBP-401547
DiGeorge syndrome critical region gene 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070413:
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:17839482-17894145
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000012152 ENSMUSP00000012152
ENSMUST00000066127 ENSMUSP00000064603
ENSMUST00000117945 ENSMUSP00000112783
ENSMUST00000117082 ENSMUSP00000113506
ENSMUST00000135229
ENSMUST00000155611
ENSMUST00000155943
ENSMUST00000126919
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007155 cell adhesion
GO:0042493 response to drug
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000070413
View Gene Order
ENSBTAG00000000429
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.254515 Mm.373829
RefSeq NM_001109750 NM_010048 XM_006521760 XM_006536795
OMIM
CCDS CCDS37276 CCDS49785
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca