InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dgcr2

Summary

InnateDB Protein

IDBP-401548.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dgcr2

Protein Name

DiGeorge syndrome critical region gene 2

Synonyms

9930034O06Rik; DGS-C; Dgsc; Idd; Lan; mKIAA0163; Sez12;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112783

InnateDB Gene

IDBG-140369 (Dgcr2)

Protein Structure

UniProt Annotation

Function

Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Ubiquitous in various organs with low abundance.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0007155	cell adhesion
GO:0042493	response to drug

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:892866

InterPro

IPR001007 von Willebrand factor, type C
IPR001304 C-type lectin
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR016187 C-type lectin fold

PFAM

PF00093
PF00059
PF00057

PRINTS

PR00261

PIRSF

SMART

SM00214
SM00034
SM00192

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt