InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc3a2

Summary

InnateDB Gene

IDBG-140475.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc3a2

Gene Name

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Synonyms

4F2; 4F2HC; AI314110; Cd98; Ly-10; Ly-m10; Ly10; Mdu1; Mgp-2hc; NACAE

Species

Mus musculus

Ensembl Gene

ENSMUSG00000010095

Encoded Proteins

IDBP-140477

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

IDBP-619900

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168003:
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:8706882-8723369

Strand

Reverse strand

Band

Transcripts

ENSMUST00000010239	ENSMUSP00000010239
ENSMUST00000170157	ENSMUSP00000130194

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003725	double-stranded RNA binding
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0015175	neutral amino acid transmembrane transporter activity
GO:0043169	cation binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0015804	neutral amino acid transport
GO:0015827	tryptophan transport
GO:0043330	response to exogenous dsRNA
GO:0060356	leucine import

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0030054	cell junction
GO:0042470	melanosome