Version 5.4
Mus musculus Gene: Tmed1
Summary
InnateDB Gene IDBG-140608.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmed1
Gene Name transmembrane emp24 domain containing 1
Synonyms Il1rl1l; Ly84l; St2l
Species Mus musculus
Ensembl Gene ENSMUSG00000032180
Encoded Proteins
IDBP-140610
transmembrane emp24 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099203:
The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1). This protein lacks any similarity to other interleukin 1 ligands. The functional significance of its interaction with IL1RL1 is not known. [provided by RefSeq, Jul 2008]
This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:21507380-21510186
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000034698 ENSMUSP00000034698
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000099203
View Gene Order
ENSBTAG00000010968
Not yet available
Cross-References
SwissProt Q3V009
TrEMBL B2RRM5
UniProt Splice Variant
Entrez Gene 17083
UniGene Mm.196618
RefSeq NM_010744
OMIM
CCDS CCDS22904
HPRD
IMGT
MGI ID MGI:106201
MGI Symbol Tmed1
EMBL AK133513 AK160525 BC138498 BC138499 CH466522 U41805
GenPept AAC52472 AAI38499 AAI38500 BAE21696 BAE35843 EDL25198
RNA Seq Atlas 17083

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca