Version 5.4
Mus musculus Gene: Nov
Summary
InnateDB Gene IDBG-140619.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nov
Gene Name nephroblastoma overexpressed gene
Synonyms C130088N23Rik; CCN3
Species Mus musculus
Ensembl Gene ENSMUSG00000037362
Encoded Proteins
IDBP-140623
nephroblastoma overexpressed gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136999:
The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:54745702-54754039
Strand Forward strand
Band D1
Transcripts
ENSMUST00000050027 ENSMUSP00000054389
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0008083 growth factor activity
Biological Process
GO:0001558 regulation of cell growth
GO:0010468 regulation of gene expression
Cellular Component
GO:0005576 extracellular region
GO:0030424 axon
GO:0030425 dendrite
GO:0031012 extracellular matrix
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136999
View Gene Order
ENSBTAG00000002080
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_3
Notch pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q64299
TrEMBL
UniProt Splice Variant
Entrez Gene 18133
UniGene Mm.398591 Mm.5167
RefSeq NM_010930
OMIM
CCDS CCDS27471
HPRD
IMGT
MGI ID MGI:109185
MGI Symbol Nov
EMBL AK039481 AK081944 BC003774 X96585 X97863 Y09257
GenPept AAH03774 BAC30363 BAC38378 CAA65404 CAA66457 CAA70454
RNA Seq Atlas 18133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca