InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nov

Summary

InnateDB Protein

IDBP-140623.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nov

Protein Name

nephroblastoma overexpressed gene

Synonyms

C130088N23Rik; CCN3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000054389

InnateDB Gene

IDBG-140619 (Nov)

Protein Structure

UniProt Annotation

Function

Immediate-early protein likely to play a role in cell growth regulation. {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005520	insulin-like growth factor binding
GO:0008083	growth factor activity

Biological Process

GO:0001558	regulation of cell growth
GO:0010468	regulation of gene expression

Cellular Component

GO:0005576	extracellular region
GO:0030424	axon
GO:0030425	dendrite
GO:0031012	extracellular matrix
GO:0043025	neuronal cell body
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:109185

InterPro

IPR000867 Insulin-like growth factor-binding protein, IGFBP
IPR000884 Thrombospondin, type 1 repeat
IPR001007 von Willebrand factor, type C
IPR006207 Cystine knot, C-terminal
IPR006208 Glycoprotein hormone subunit beta, cystine knot
IPR012395 IGFBP-related, CNN

PFAM

PF00219
PF00090
PF00093
PF00007

PRINTS

PIRSF

PIRSF036495

SMART

SM00121
SM00209
SM00214
SM00041

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt