InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rab23

Summary

InnateDB Gene

IDBG-140627.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab23

Gene Name

RAB23, member RAS oncogene family

Synonyms

AW545388; opb; opb2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000004768

Encoded Proteins

IDBP-140629

RAB23, member RAS oncogene family

IDBP-250199

RAB23, member RAS oncogene family

IDBP-714150

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112210:
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:33719887-33742564

Strand

Forward strand

Band

Transcripts

ENSMUST00000088287	ENSMUSP00000085625
ENSMUST00000115174	ENSMUSP00000110828
ENSMUST00000140354
ENSMUST00000138024	ENSMUSP00000137896
ENSMUST00000135330
ENSMUST00000151482
ENSMUST00000150593
ENSMUST00000122822
ENSMUST00000132066

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding

Biological Process

GO:0000045	autophagic vacuole assembly
GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0006968	cellular defense response
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0007399	nervous system development
GO:0008589	regulation of smoothened signaling pathway
GO:0015031	protein transport
GO:0021513	spinal cord dorsal/ventral patterning
GO:0042733	embryonic digit morphogenesis
GO:0042992	negative regulation of transcription factor import into nucleus
GO:0045861	negative regulation of proteolysis
GO:0097094	craniofacial suture morphogenesis

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005776	autophagic vacuole
GO:0016020	membrane
GO:0045335	phagocytic vesicle
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000112210

View Gene Order

ENSBTAG00000005362

Not yet available

Pathways

NETPATH

REACTOME

KEGG

mmu04340

Hedgehog signaling pathway pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

NetPath_10

Hedgehog pathway

REACTOME

KEGG

hsa04340

Hedgehog signaling pathway pathway

INOH

PID NCI

hedgehog_glipathway

Hedgehog signaling events mediated by Gli proteins

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.86744

RefSeq

NM_001159729 NM_008999 XM_006495801 XM_006495802

OMIM

CCDS

CCDS35532

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas