Version 5.4
Mus musculus Gene: Prss2
Summary
InnateDB Gene IDBG-140691.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prss2
Gene Name protease, serine, 2
Synonyms Ta; Tesp4; Try2; TRY8; TRYP
Species Mus musculus
Ensembl Gene ENSMUSG00000057163
Encoded Proteins
IDBP-140693
protease, serine, 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:41521787-41525079
Strand Forward strand
Band B1
Transcripts
ENSMUST00000070380 ENSMUSP00000065393
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
GO:0007584 response to nutrient
GO:0007586 digestion
GO:0010033 response to organic substance
GO:0030574 collagen catabolic process
GO:0031000 response to caffeine
GO:0035094 response to nicotine
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_199049
Defensins pathway
REACT_239142
Innate Immune System pathway
REACT_260145
Alpha-defensins pathway
REACT_199000
Activation of Matrix Metalloproteinases pathway
REACT_230745
Immune System pathway
REACT_206066
Extracellular matrix organization pathway
REACT_199052
Degradation of the extracellular matrix pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
mmu04974
Protein digestion and absorption pathway
mmu04972
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt P07146
TrEMBL Q792Y6
UniProt Splice Variant
Entrez Gene 22072
UniGene
RefSeq NM_009430
OMIM
CCDS CCDS20050
HPRD
IMGT
MGI ID MGI:102759
MGI Symbol Prss2
EMBL AB017030 AE000665 AK003082 CH466533 X04574 X04577
GenPept AAB69089 BAA74759 BAB22554 CAA28243 CAA28245 EDL13530
RNA Seq Atlas 22072

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca