InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prss2

Summary

InnateDB Protein

IDBP-140693.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prss2

Protein Name

protease, serine, 2

Synonyms

Ta; Tesp4; Try2; TRY8; TRYP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000065393

InnateDB Gene

IDBG-140691 (Prss2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted, extracellular space.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005509	calcium ion binding

Biological Process

GO:0006508	proteolysis
GO:0007584	response to nutrient
GO:0007586	digestion
GO:0010033	response to organic substance
GO:0030574	collagen catabolic process
GO:0031000	response to caffeine
GO:0035094	response to nicotine

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space

Protein Structure and Domains

PDB ID

MGI:102759

InterPro

IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain

PFAM

PF00089

PRINTS

PR00722

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P07146

PhosphoSite

PhosphoSite-

TrEMBL

Q792Y6

UniProt Splice Variant

Entrez Gene

22072

UniGene

RefSeq

NP_033456

MGI ID

MGI Symbol

Prss2

OMIM

CCDS

CCDS20050

HPRD

IMGT

EMBL

AB017030 AE000665 AK003082 CH466533 X04574 X04577

GenPept

AAB69089 BAA74759 BAB22554 CAA28243 CAA28245 EDL13530