Version 5.4
Mus musculus Gene: Slc20a2
Summary
InnateDB Gene IDBG-140771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc20a2
Gene Name solute carrier family 20, member 2
Synonyms MolPit2; Pit-2; Pit2; Ram-1; Ram1
Species Mus musculus
Ensembl Gene ENSMUSG00000037656
Encoded Proteins
IDBP-140773
solute carrier family 20, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168575:
This gene encodes a member of the inorganic phosphate transporter family. The encoded protein is a type 3 sodium-dependent phosphate symporter that plays an important role in phosphate homeostasis by mediating cellular phosphate uptake. The encoded protein also confers susceptibility to viral infection as a gamma-retroviral receptor. Mutations in this gene may play a role in familial idiopathic basal ganglia calcification. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:22476700-22569607
Strand Forward strand
Band A2
Transcripts
ENSMUST00000067786 ENSMUSP00000065935
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005315 inorganic phosphate transmembrane transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006817 phosphate ion transport
GO:0016032 viral process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168575
View Gene Order
ENSBTAG00000014861
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_256507
Sodium-coupled phosphate cotransporters pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19275
Sodium-coupled phosphate cotransporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q80UP8
TrEMBL P70456
UniProt Splice Variant
Entrez Gene 20516
UniGene Mm.323901 Mm.408526
RefSeq NM_011394 XM_006509043 XM_006509044
OMIM
CCDS CCDS22178
HPRD
IMGT
MGI ID MGI:97851
MGI Symbol Slc20a2
EMBL AC140326 AC153017 AF196476 AK157206 AK170985 BC046510 U62560
GenPept AAB06047 AAG28493 AAH46510 BAE33999 BAE42159
RNA Seq Atlas 20516

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca