InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc25a1

Summary

InnateDB Gene

IDBG-140853.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc25a1

Gene Name

solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1

Synonyms

1300019P08Rik; 2610100G11Rik; AI194714; Ctp; Dgsj; Slc20a3

Species

Mus musculus

Ensembl Gene

ENSMUSG00000003528

Encoded Proteins

IDBP-140855

solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1

IDBP-540323

solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100075:
The mitochondrial tricarboxylate transporter (also called citrate transport protein, or CTP) is responsible for the movement of citrate across the mitochondrial inner membrane (Kaplan et al., 1993 [PubMed 8514800]).[supplied by OMIM, Jan 2011]
This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7, 11, 16, and 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:17925211-17928219

Strand

Reverse strand

Band

Transcripts

ENSMUST00000003622	ENSMUSP00000003622
ENSMUST00000129270
ENSMUST00000131507	ENSMUSP00000123613
ENSMUST00000150925
ENSMUST00000142022
ENSMUST00000147384

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0055085

transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome