Version 5.4
Mus musculus Gene: Vpreb2
Summary
InnateDB Gene IDBG-140903.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vpreb2
Gene Name pre-B lymphocyte gene 2
Synonyms CD179b; Vpreb-2; VpreB1
Species Mus musculus
Ensembl Gene ENSMUSG00000059280
Encoded Proteins
IDBP-140905
pre-B lymphocyte gene 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169575:
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:17980565-17981080
Strand Forward strand
Band A3
Transcripts
ENSMUST00000075371 ENSMUSP00000074835
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0008361 regulation of cell size
GO:0042100 B cell proliferation
GO:0048872 homeostasis of number of cells
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169575
View Gene Order
ENSBTAG00000017305
Not yet available
Cross-References
SwissProt P13373
TrEMBL
UniProt Splice Variant
Entrez Gene 22363
UniGene Mm.377118
RefSeq NM_016983 XM_006522011 XM_006522012
OMIM
CCDS CCDS28015
HPRD
IMGT
MGI ID MGI:98937
MGI Symbol Vpreb2
EMBL X05563
GenPept CAA29077
RNA Seq Atlas 22363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca