Version 5.4
Mus musculus Protein: Vpreb2
Summary
InnateDB Protein IDBP-140905.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vpreb2
Protein Name pre-B lymphocyte gene 2
Synonyms CD179b; Vpreb-2; VpreB1;
Species Mus musculus
Ensembl Protein ENSMUSP00000074835
InnateDB Gene IDBG-140903 (Vpreb2)
Protein Structure
UniProt Annotation
Function Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.
Subcellular Localization
Disease Associations
Tissue Specificity Only expressed by pre-B-cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0008361 regulation of cell size
GO:0042100 B cell proliferation
GO:0048872 homeostasis of number of cells
Cellular Component
Protein Structure and Domains
PDB ID MGI:98937
InterPro IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00406
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P13373
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 22363
UniGene Mm.377118
RefSeq NP_058679
MGI ID
MGI Symbol Vpreb2
OMIM
CCDS CCDS28015
HPRD
IMGT
EMBL X05563
GenPept CAA29077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca