Version 5.4
Mus musculus Gene: Agap3
Summary
InnateDB Gene IDBG-141498.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agap3
Gene Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000023353
Encoded Proteins
IDBP-141500
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133612:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:24452177-24502047
Strand Forward strand
Band A3
Transcripts
ENSMUST00000024123 ENSMUSP00000024123
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0031593 polyubiquitin binding
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0030578 PML body organization
GO:0032312 regulation of ARF GTPase activity
GO:0034614 cellular response to reactive oxygen species
GO:0034644 cellular response to UV
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016605 PML body
GO:0071944 cell periphery
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000133612
View Gene Order
ENSBTAG00000008468
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8VQE9 Q8BV81
UniProt Splice Variant
Entrez Gene 213990
UniGene Mm.250703
RefSeq NM_139153 XM_006535677
OMIM
CCDS CCDS19122
HPRD
IMGT
MGI ID MGI:2183446
MGI Symbol Agap3
EMBL AC120353 AK079516
GenPept BAC37668
RNA Seq Atlas 213990

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca