Mus musculus Gene: Pcdh12
Summary
InnateDB Gene IDBG-141574.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdh12
Gene Name protocadherin 12
Synonyms Pcdh14; VE-cad-2
Species Mus musculus
Ensembl Gene ENSMUSG00000024440
Encoded Proteins
protocadherin 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113555:
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:38267092-38284401
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000025311 ENSMUSP00000025311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0005977 glycogen metabolic process
GO:0007156 homophilic cell adhesion
GO:0016339 calcium-dependent cell-cell adhesion
GO:0060711 labyrinthine layer development
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt O55134
TrEMBL A0JNZ2
UniProt Splice Variant
Entrez Gene 53601
UniGene Mm.12862
RefSeq NM_017378
OMIM
CCDS CCDS29199
HPRD
IMGT
MGI ID MGI:1855700
MGI Symbol Pcdh12
EMBL AC133646 AC152450 BC127076 CH466528 Y08715
GenPept AAI27077 CAA69965 EDL10091 EDL10092
RNA Seq Atlas 53601