Version 5.4
Bos taurus Gene: PCDH12
Summary
InnateDB Gene IDBG-646124.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDH12
Gene Name protocadherin-12 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008437
Encoded Proteins
IDBP-698899
protocadherin-12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113555:
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:54690461-54702923
Strand Reverse strand
Band
Transcripts
ENSBTAT00000011099 ENSBTAP00000011099
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0005977 glycogen metabolic process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0016339 calcium-dependent cell-cell adhesion
GO:0060711 labyrinthine layer development
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000113555
View Gene Order
ENSMUSG00000024440
View Gene Order
Cross-References
SwissProt
TrEMBL F1N0X0
UniProt Splice Variant
Entrez Gene 540115
UniGene Bt.6961
RefSeq NM_001098111 XM_005209471 XM_005209472
HUGO HGNC:8657
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020447
GenPept
RNA Seq Atlas 540115

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca