Mus musculus Gene: Arvcf | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-141624.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Arvcf | ||||||||||||||||||||||
Gene Name | armadillo repeat gene deleted in velo-cardio-facial syndrome | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000000325 | ||||||||||||||||||||||
Encoded Proteins |
armadillo repeat gene deleted in velo-cardio-facial syndrome
armadillo repeat gene deleted in velo-cardio-facial syndrome
armadillo repeat gene deleted in velo-cardio-facial syndrome
armadillo repeat gene deleted in velo-cardio-facial syndrome
armadillo repeat gene deleted in velo-cardio-facial syndrome
armadillo repeat gene deleted in velo-cardio-facial syndrome
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099889:
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 16:18348182-18407076 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | A3 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | D6RI19 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 11877 | ||||||||||||||||||||||
UniGene | Mm.293599 Mm.403331 | ||||||||||||||||||||||
RefSeq | NM_001272028 NM_001272029 NM_001272030 NM_001272031 NM_001272032 NM_033474 XM_006521719 XM_006536859 XM_006536860 XM_006544939 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS28020 CCDS70693 CCDS70694 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:109620 | ||||||||||||||||||||||
MGI Symbol | Arvcf | ||||||||||||||||||||||
EMBL | AC084822 AC133487 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 11877 | ||||||||||||||||||||||