InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Mastl

Summary

InnateDB Gene

IDBG-141639.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mastl

Gene Name

microtubule associated serine/threonine kinase-like

Synonyms

2700091H24Rik; C88295; GW; GWL; MAST-L; THC2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026779

Encoded Proteins

IDBP-141641

microtubule associated serine/threonine kinase-like

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120539:
This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:23115606-23156024

Strand

Reverse strand

Band

Transcripts

ENSMUST00000028119	ENSMUSP00000028119
ENSMUST00000136207

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0051721	protein phosphatase 2A binding

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0006468	protein phosphorylation
GO:0006974	cellular response to DNA damage stimulus
GO:0007067	mitotic nuclear division
GO:0034048	negative regulation of protein phosphatase type 2A activity
GO:0051726	regulation of cell cycle