Version 5.4
| Mus musculus Gene: Cacna2d3 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-141723.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Cacna2d3 | ||||||
| Gene Name | calcium channel, voltage-dependent, alpha2/delta subunit 3 | ||||||
| Synonyms | Cacnad3 | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000021991 | ||||||
| Encoded Proteins |
calcium channel, voltage-dependent, alpha2/delta subunit 3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157445:
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 14:28904943-29721864 | ||||||
| Strand | Reverse strand | ||||||
| Band | A3 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
MAPK signaling pathway pathway
Cardiac muscle contraction pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Neuronal System pathway
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels pathway
Transmission across Chemical Synapses pathway
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| KEGG |
MAPK signaling pathway pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Cardiac muscle contraction pathway
Dilated cardiomyopathy pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q9Z1L5 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 12294 | ||||||
| UniGene | Mm.386754 Mm.488024 | ||||||
| RefSeq | NM_009785 XM_006518486 XM_006518487 | ||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1338890 | ||||||
| MGI Symbol | Cacna2d3 | ||||||
| EMBL | AJ010949 | ||||||
| GenPept | CAA09423 | ||||||
| RNA Seq Atlas | 12294 | ||||||