Homo sapiens Gene: KLB | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-14182.6 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | KLB | ||||||||||||||||||||
Gene Name | klotho beta | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||
Ensembl Gene | ENSG00000134962 | ||||||||||||||||||||
Encoded Proteins |
klotho beta
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary | Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs. | ||||||||||||||||||||
Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 4:39406853-39451536 | ||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||
Band | p14 | ||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
PIP3 activates AKT signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
PI3K/AKT activation pathway
GAB1 signalosome pathway
Signaling by EGFR pathway
PI3K events in ERBB4 signaling pathway
Signaling by ERBB4 pathway
PI3K Cascade pathway
Signaling by Insulin receptor pathway
IRS-related events triggered by IGF1R pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
PI3K events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
Negative regulation of FGFR signaling pathway
Phospholipase C-mediated cascade pathway
SHC-mediated cascade pathway
PI-3K cascade pathway
FRS2-mediated cascade pathway
betaKlotho-mediated ligand binding pathway
Signaling by FGFR pathway
Signaling by SCF-KIT pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
Signaling by FGFR in disease pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
IRS-mediated signalling pathway
Adaptive Immune System pathway
Immune System pathway
Insulin receptor signalling cascade pathway
Klotho-mediated ligand binding pathway
NGF signalling via TRKA from the plasma membrane pathway
IRS-related events pathway
IGF1R signaling cascade pathway
PI3K/AKT Signaling in Cancer pathway
FGFR ligand binding and activation pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
Disease pathway
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KEGG | |||||||||||||||||||||
INOH | |||||||||||||||||||||
PID NCI |
FGF signaling pathway
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Cross-References | |||||||||||||||||||||
SwissProt | Q86Z14 | ||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 152831 | ||||||||||||||||||||
UniGene | Hs.90756 | ||||||||||||||||||||
RefSeq | NM_175737 | ||||||||||||||||||||
HUGO | HGNC:15527 | ||||||||||||||||||||
OMIM | 611135 | ||||||||||||||||||||
CCDS | CCDS3451 | ||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | AB079373 BC104871 BC113653 | ||||||||||||||||||||
GenPept | AAI04872 AAI13654 BAC56857 | ||||||||||||||||||||
RNA Seq Atlas | 152831 | ||||||||||||||||||||