Version 5.4
Mus musculus Gene: Nkx6-3
Summary
InnateDB Gene IDBG-141902.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nkx6-3
Gene Name NK6 homeobox 3
Synonyms 9130417I07Rik; Nkx6.3
Species Mus musculus
Ensembl Gene ENSMUSG00000063672
Encoded Proteins
IDBP-141904
NK6 homeobox 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165066:
The NKX family of homeodomain proteins controls numerous developmental processes. Members of the NKX6 subfamily, including NKX6-3, are involved in development of the central nervous system (CNS), gastrointestinal tract, and pancreas (Alanentalo et al., 2006 [PubMed 16326147]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:23153269-23158948
Strand Forward strand
Band A2
Transcripts
ENSMUST00000071588 ENSMUSP00000071517
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001709 cell fate determination
GO:0002067 glandular epithelial cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030857 negative regulation of epithelial cell differentiation
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165066
View Gene Order
ENSBTAG00000018495
Not yet available
Cross-References
SwissProt Q3UHX8
TrEMBL B2RU70
UniProt Splice Variant
Entrez Gene 74561
UniGene Mm.290028
RefSeq NM_029002
OMIM
CCDS CCDS52524
HPRD
IMGT
MGI ID MGI:1921811
MGI Symbol Nkx6-3
EMBL AK018683 AK147163 BC140994 CH466580 DQ093570
GenPept AAI40995 AAY98485 BAB31342 BAE27728 EDL32869
RNA Seq Atlas 74561

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca