InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nkx6-3

Summary

InnateDB Protein

IDBP-141904.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nkx6-3

Protein Name

NK6 homeobox 3

Synonyms

9130417I07Rik; Nkx6.3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000071517

InnateDB Gene

IDBG-141902 (Nkx6-3)

Protein Structure

UniProt Annotation

Function

Putative transcription factor, which may be involved in patterning of central nervous system and pancreas. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.

Disease Associations

Tissue Specificity

Expressed in the developing CNS and gastro- intestinal tract. {ECO:0000269PubMed:16326147}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001709	cell fate determination
GO:0002067	glandular epithelial cell differentiation
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030857	negative regulation of epithelial cell differentiation