Mus musculus Gene: Agpat6
Summary
InnateDB Gene IDBG-141928.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agpat6
Gene Name 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
Synonyms AU041707; AW545732; GPAT4; Tsarg7
Species Mus musculus
Ensembl Gene ENSMUSG00000031545
Encoded Proteins
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158669:
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:23172946-23208453
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000167004 ENSMUSP00000127325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004366 glycerol-3-phosphate O-acyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0002071 glandular epithelial cell maturation
GO:0006631 fatty acid metabolic process
GO:0006637 acyl-CoA metabolic process
GO:0006641 triglyceride metabolic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0007595 lactation
GO:0008152 metabolic process
GO:0008610 lipid biosynthetic process
GO:0016024 CDP-diacylglycerol biosynthetic process
GO:0019432 triglyceride biosynthetic process
GO:0030879 mammary gland development
GO:0040014 regulation of multicellular organism growth
GO:0046339 diacylglycerol metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Triglyceride Biosynthesis pathway
Glycerophospholipid biosynthesis pathway
Synthesis of PA pathway
Phospholipid metabolism pathway
KEGG
Glycerophospholipid metabolism pathway
Glycerolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of PA pathway
Triglyceride Biosynthesis pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
KEGG
Glycerophospholipid metabolism pathway
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q8K2C8
TrEMBL Q3TSI4 Q6PEU9
UniProt Splice Variant
Entrez Gene 102247
UniGene Mm.200898
RefSeq NM_018743
OMIM
CCDS CCDS22189
HPRD
IMGT
MGI ID MGI:2142716
MGI Symbol Agpat6
EMBL AF406611 AK045235 AK077561 AK083589 AK161270 AK162033 AK169257 BC031767 BC057860
GenPept AAH31767 AAH57860 AAP97283 BAC32273 BAC36864 BAC38962 BAE36282 BAE36691 BAE41020
RNA Seq Atlas 102247