Version 5.4
Mus musculus Gene: Chdh
Summary
InnateDB Gene IDBG-142274.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chdh
Gene Name choline dehydrogenase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000015970
Encoded Proteins
IDBP-142276
choline dehydrogenase
IDBP-401602
choline dehydrogenase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000016391:
The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:30009023-30040466
Strand Forward strand
Band B
Transcripts
ENSMUST00000067620 ENSMUSP00000065542
ENSMUST00000118917 ENSMUSP00000112916
ENSMUST00000125796
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008812 choline dehydrogenase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006066 alcohol metabolic process
GO:0016117 carotenoid biosynthetic process
GO:0019285 glycine betaine biosynthetic process from choline
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000016391
View Gene Order
ENSBTAG00000010027
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00260
Glycine, serine and threonine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00260
Glycine, serine and threonine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q8BJ64
TrEMBL
UniProt Splice Variant
Entrez Gene 218865
UniGene Mm.259916 Mm.402200
RefSeq NM_001136240 NM_172264 NM_175343
OMIM
CCDS CCDS26892
HPRD
IMGT
MGI ID MGI:1860776
MGI Symbol Chdh
EMBL AK030900 AK164042 BC039186
GenPept AAH39186 BAC27176 BAE37601
RNA Seq Atlas 218865

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca