InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Chdh

Summary

InnateDB Protein

IDBP-401602.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Chdh

Protein Name

choline dehydrogenase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112916

InnateDB Gene

IDBG-142274 (Chdh)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion inner membrane {ECO:0000269PubMed:20371614}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008812	choline dehydrogenase activity
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0006066	alcohol metabolic process
GO:0016117	carotenoid biosynthetic process
GO:0019285	glycine betaine biosynthetic process from choline
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane

Protein Structure and Domains

PDB ID

MGI:1860776

InterPro

IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal
IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal
IPR008671 Lycopene cyclase-type, FAD-binding
IPR011533 Oxygen-dependent choline dehydrogenase
IPR012132 Glucose-methanol-choline oxidoreductase

PFAM

PF00732
PF05199
PF05834

PRINTS

PIRSF

PIRSF000137

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BJ64